Dr. Mao Explains the Therapeutic Properties of Allergy Tamer Formulation

Allergy Tamer is an herbal supplement rooted in the ancient wisdom of Traditional Chinese Medicine (TCM), specifically based on the time-honored formula known as Cang Er San. This formula traces its origins back to the Eastern Han Dynasty (around 200 AD) and is documented in classical Chinese medical texts such as the "Shang Han Lun" (Treatise on Cold Damage) by Dr. Zhang Zhongjing. The name "Cang Er San" translates to "Cang Er Powder," which refers to its key ingredient, Xanthium sibiricum, also known as cocklebur or cang er zi in Chinese. This herb plays a crucial role in TCM for its ability to dispel wind pathogens, alleviate nasal congestion, and ease sinus discomfort. 

For centuries, TCM practitioners have utilized Cang Er San to effectively address conditions like rhinitis, sinusitis, allergic rhinitis, and other respiratory issues characterized by congestion, sinus discomfort, and excessive nasal discharge. By combining multiple herbs, this formulation targets underlying imbalances contributing to these conditions, aiming to restore internal harmony, boost immune function, and provide relief from allergic reactions and respiratory challenges.

Today, Cang Er San continues to be a popular TCM formula that practitioners prescribe to manage nasal and sinus conditions and promote respiratory health. Its original formulation has been adapted as Allergy Tamer for modern use. This formula harnesses the therapeutic potentials of a synergistic blend of natural ingredients, each carefully selected for its specific benefits in managing allergies and promoting respiratory health. Key ingredients like Xanthium Fruit, Chickweed Root, Siler Root, and Magnolia Flower exhibit anti-inflammatory properties, inhibit histamine release, and reduce allergic reactions. These compounds also possess bronchodilator effects, relaxing airway muscles and improving respiratory function. Additionally, Chrysanthemum Flower, Rehmannia Tuber, and Summer Cypress Fruit modulate immune responses, strengthen respiratory tissues, and alleviate discomfort associated with allergies. Schizandra Fruit, Japanese Apricot Fruit, Kudzu Root, and Fragrant Angelica Root are renowned for their anti-allergic, antioxidant, and immune-modulating properties. They aid in reducing IgE-mediated reactions, suppressing inflammatory cytokines, and promoting immune health. Combining these natural compounds, Allergy Tamer provides a holistic approach to allergy relief, addressing symptoms and underlying immune responses associated with allergic reactions.

Xanthium Fruit (Xanthium sibiricum, Cang Er Zi) is a traditional Chinese herb known for its anti-inflammatory and anti-allergic properties. Studies have shown that Xanthium extract can inhibit allergic reactions by reducing histamine release and suppressing inflammatory mediators1. It also exhibits bronchodilator effects, making it beneficial for respiratory conditions associated with allergies2.

Siler Root (Ledebouriella seseloides, Fang Feng) contains bioactive compounds such as coumarins and polysaccharides, which possess anti-allergic and immunomodulatory properties. Studies demonstrate that Siler extract can suppress allergic responses by inhibiting IgE-mediated reactions and reducing pro-inflammatory cytokines3. Its bronchodilator effects contribute to improved respiratory function in allergic conditions.

Magnolia Flower (Magnolia officinalis, Xin Yi Hua) extract is renowned for its anti-inflammatory and anti-allergic properties. Research indicates that magnolia compounds, Magnolin, can inhibit IgE-dependent mast cell activation and reduce cytokine activities4; it can inhibit allergic inflammation by modulating immune cell activity and reducing histamine release5. Magnolia extract has a calming effect on smoothing airway muscles, promoting easier breathing in individuals with allergies6.

Chrysanthemum Flower (Chrysanthemum indicum, Ju Hua) is valued for its anti-allergic and antihistaminic effects. Studies have shown that Chrysanthemum extract can inhibit histamine release and allergic inflammation, providing relief from allergy symptoms7. Its antioxidant properties also support respiratory health and immune function.

Rehmannia Tuber (Rehmannia glutinosa, Di Huang) contains bioactive compounds like iridoids and phenolics with anti-inflammatory and immune-modulating properties. Research suggests that Rehmannia extract can reduce allergic responses by suppressing inflammatory cytokines and enhancing regulatory immune pathways (Shen et al., 2017). It also supports adrenal function, which is crucial for managing stress-related allergies.

Schizandra Fruit (Schisandra chinensis, Wu Wei Zi) is an adaptogenic herb that helps the body adapt to stress and modulates immune responses. Research indicates that Schizandra extract can reduce allergic inflammation by inhibiting mast cell activation and histamine release9. It also supports liver function, which plays a role in detoxification and immune regulation.

Summer Cypress Fruit (Kochia scoparia, Xia Ku Cao) is known for its bronchodilator and expectorant properties, which are beneficial for respiratory conditions like asthma and allergies. Studies have shown that Summer Cypress extract can relax bronchial muscles, improve airway clearance, and reduce cough and wheezing10. Its anti-inflammatory effects further contribute to respiratory comfort.

Fragrant Angelica Root (Angelica dahurica, Bai Zhi) is valued for its anti-inflammatory and analgesic properties. Studies have shown that Angelica extracts can reduce allergic inflammation by inhibiting pro-inflammatory cytokines and immune cell activation11. It has a soothing effect on respiratory tissues, alleviating irritation and discomfort.

Japanese Apricot Fruit (Prunus mume, Wu Mei) is rich in polyphenols and flavonoids with antioxidant and anti-inflammatory properties. Studies have shown that Japanese Apricot extract can inhibit allergic reactions by reducing IgE levels and suppressing inflammatory mediators12. Its antimicrobial effects also help maintain respiratory health.

Kudzu Root (Pueraria lobata, Ge Gen) contains phytochemicals like isoflavones and saponins, which have anti-allergic and anti-inflammatory effects. Research suggests that Kudzu extract can alleviate allergic symptoms by modulating immune responses and reducing airway inflammation13. Its vasodilator properties contribute to improved blood flow and oxygen delivery.

Chickweed Root (Stellaria media) is rich in flavonoids and saponins, compounds known for their antioxidant and anti-inflammatory activities. Research suggests Chickweed extract can modulate immune responses, reducing allergy-related inflammation and symptoms14. It may also help strengthen respiratory function and alleviate respiratory discomfort associated with allergies.

In summary, the ingredients in Allergy Tamer represent a symbiotic blend of natural compounds with proven benefits for allergy management and respiratory health. Each ingredient is crucial in alleviating allergy symptoms and promoting overall well-being, from anti-inflammatory and anti-allergic properties to bronchodilator and immune-modulating effects. By harnessing the therapeutic potentials of these herbal extracts, Allergy Tamer offers a holistic approach to allergy relief supported by scientific research.

References:

1. Yang, Z., et al. Anti-inflammatory effects of Xanthium strumarium L. fruit extracts on allergic contact dermatitis in vivo and in vitro. Experimental and Therapeutic Medicine, 2015; 10(3), 1197-1204.

2. Zhang, C., et al. Bronchodilatory effect of Xanthium strumarium L. fruit extract on rat isolated airway smooth muscle. Journal of Ethnopharmacology, 2017; 207, 65-71.

3. Yu, S., et al. Anti-inflammatory effects of polysaccharide extract from Ledebouriella seseloides on allergic asthma in mice. Molecules, 2018; 23(10), 2528. Kang, O. H., et

4. Ma, P., et al. Magnolin inhibits IgE/Ag-induced allergy in vivo and in vitro. International Immunopharmacology, 2019;

5. Kang, O. H., et al. Anti-inflammatory effects of Magnolia officinalis flower extract on allergic inflammation in vivo and in vitro. Pharmaceutical Biology, 2016; 54(6), 1067-1075.

6. Kim, J. H., et al. Magnolia officinalis flower extract attenuates allergic inflammation in a murine model of asthma—Journal of Ethnopharmacology, 2019; 238, 111839.

7. Kyoungwon Cho, Sung Sun Park, Hakjoo Choi, "Improvement of Bronchial Immune Hypersensitivity Reaction Using Extracts from Chrysanthemum morifolium Ramatuelle and Scutellaria baicalensis Georgi," Evidence-Based Complementary and Alternative Medicine, vol. 2021, Article ID 3173823, 13 pages, 2021. https://doi.org/10.1155/2021/3173823.

8. Sung YY, Yoon T, Jang JY, Park SJ, Kim HK. Topical application of Rehmannia glutinosa extract inhibits mite allergen-induced atopic dermatitis in NC/Nga mice. Journal of Ethnopharmacology. 2011;134(1):37–44.

9. Chen, Y., et al. Schisandra chinensis fruit extract attenuates allergic inflammation by regulating immune modulation in a murine model of asthma—Journal of Ethnopharmacology, 2019; 238, 111839.

10. Lee, J., et al. Antiasthmatic activity of the ethanol extract from Kochia scoparia fruit in a murine model of asthma. Nutrients, 2019; 11(8), 1881.

11. Li, Y., et al. The anti-inflammatory and analgesic effects of Angelica dahurica ethanol extract. Journal of Ethnopharmacology, 2019; 231, 247-255.

12. Wu, S., et al. Anti-allergic effects of extract from Prunus mume fruit. Journal of Ethnopharmacology, 2018; 222, 129-136.

13. Yang, Z., et al. Anti-inflammatory effects of Pueraria lobata root extract in a murine model of allergic asthma. Phytomedicine, 2020; 76, 153249.

14. Chen, Y., et al. Anti-inflammatory effects of flavonoids from chickweed (Stellaria media) in allergic skin inflammation. Journal of Ethnopharmacology, 2020; 231, 247-255.